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Drug-resistant TB
TB drug trial yields gains in drug-resistant disease treatment

A study following patients who had participated in a trial of a potential new treatment for drug-resistant tuberculosis has shown heartening results, with nearly three-quarters of patients who took the medicine for six months or longer showing “favorable outcomes” — cured or completed treatment – according to a study published in the European Respiratory Journal.

Published
02 October 2012
From
Science Speaks
TB treatment
Sanofi and TB Alliance Announce Collaboration to Accelerate New Treatments Against Tuberculosis

Sanofi and the Global Alliance for TB Drug Development (TB Alliance) announced today a new research collaboration agreement to accelerate the discovery and development of novel compounds against tuberculosis (TB), a deadly infectious disease that resulted in almost 1.5 million deaths worldwide1 in 2010.

Published
21 September 2012
From
TB Alliance
Tuberculosis and HIV
TB control – a “common responsibility”, says ECDC Director

“We must embrace the concept of common responsibility between high burden and low burden countries, creating a platform for a truly global action against TB’, concluded the ECDC Director. ‘This is why I am particularly pleased that ECDC and the European Respiratory Society have developed 21 patient-centred standards that aim to guide clinicians and public health workers in their daily work to ensure optimal diagnosis, treatment and prevention of TB in the EU”.

Published
04 September 2012
From
ECDC press release
Drug-resistant TB
Janssen-Cilag International NV (Janssen) Submits European Marketing Authorisation Application for Investigational Multi-Drug Resistant Tuberculosis Treatment Bedaquiline

If approved, bedaquiline (Ba-DA-qui-lin) could be one of the first drugs with a new mechanism of action for tuberculosis (TB) in more than 40 years and one of the first ever to be specifically indicated for MDR-TB.

Published
03 September 2012
From
Janssen-Cilag press release
Drug-resistant TB
International study finds "worrying" levels of XDR-TB

Results of an international study published in The Lancet show that 7% of people receiving second-line treatment for tuberculosis (TB) have extensively drug-resistant TB (XDR-TB). The investigators describe

Published
31 August 2012
By
Michael Carter
TB treatment
HIV testing, HIV status and outcomes of treatment for tuberculosis in a major diagnosis and treatment centre in Yaounde, Cameroon: a retrospective cohort study

In a major TB diagnosis and treatment centre in Cameroon, not testing for HIV was associated with 2.3 times the risk of death or TB treatment failure. Link to full text of paper available.

Published
16 August 2012
From
Biomed Central
TB treatment
Raltegravir 800mg twice daily appears a good alternative to efavirenz for HIV-TB treatment

Raltegravir seems to be a suitable alternative to efavirenz for HIV-TB co-infected patients while receiving TB treatment, according to 24-week results of the ANRS 12 180 REFLATE

Published
31 July 2012
By
Lesley Odendal
TB treatment
Tuberculosis: Combined wisdom

Buried in the HIV frenzy at the International AIDS Conference was a rather important announcement for another blight, tuberculosis.

Published
26 July 2012
From
The Economist
TB treatment
Novel TB combination regimen shows potent activity in randomised short-term clinical trial

A new TB drug, PA-824, showed very potent early bactericidal activity in a randomised 14-day study in people with TB, when used in combination with the established antibiotic

Published
25 July 2012
By
Theo Smart
HIV treatment in children
Efavirenz Works in Kids with Both HIV and TB

Children co-infected with HIV and tuberculosis appear to suppress both infections when treated with standard TB regimens and an efavirenz-based HIV regimen, researchers said here at the International AIDS Conference.

Published
25 July 2012
From
MedPage Today HIV/AIDS
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